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Novel ABCG2 antagonists reverse topotecan-mediated chemotherapeutic resistance in ovarian carcinoma xenografts

Chemotherapeutic resistance remains a challenge in the treatment of ovarian carcinoma, especially in recurrent disease. Despite the fact that most patients with newly diagnosed tumors attain complete remission following cytoreductive surgery and chemotherapy, ovarian carcinoma has a recurrence rate...

詳細記述

保存先:
書誌詳細
出版年:Mol Cancer Ther
主要な著者: Ricci, Jerec W., Lovato, Debbie M., Severns, Virginia, Sklar, Larry A., Larson, Richard S.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5136347/
https://ncbi.nlm.nih.gov/pubmed/27671528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-15-0789
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