Anti-angiogenic properties of metronomic topotecan in ovarian carcinoma

Purpose: Metronomic chemotherapy regimens have shown anti-tumor activity by anti-angiogenic mechanisms, however, the efficacy of metronomic topotecan in ovarian cancer is not known and the focus of the current study.   Experimental Design: In vivo dose-finding and therapy experiments with oral metro...

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Main Authors: Merritt, William M., Danes, Christopher G., Shahzad, Mian M.K., Lin, Yvonne G., Kamat, Aparna A., Han, Liz Y., Spannuth, Whitney A., Nick, Alpa M., Mangala, Lingegowda S., Stone, Rebecca L., Kim, Hye Sun, Gershenson, David M., Jaffe, Robert B., Coleman, Robert L., Chandra, Joya, Sood, Anil K.
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2009
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916970/
https://ncbi.nlm.nih.gov/pubmed/19738426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.8.16.9004
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