Dual metronomic chemotherapy with nab-paclitaxel and topotecan has potent anti-angiogenic activity in ovarian cancer

There is growing recognition of the important role of metronomic chemotherapy in cancer treatment. On the basis of their unique anti-angiogenic effects, we tested the efficacy of nab-paclitaxel, which stimulates thrombospondin-1, and topotecan, which inhibits hypoxia-inducible factor 1-α, at metrono...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Previs, Rebecca A., Armaiz-Pena, Guillermo N., Lin, Yvonne G., Davis, Ashley N., Pradeep, Sunila, Dalton, Heather J., Hansen, Jean M., Merritt, William M., Nick, Alpa M., Langley, Robert R., Coleman, Robert L., Sood, Anil K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674355/
https://ncbi.nlm.nih.gov/pubmed/26516159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-14-0630
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