Anti-angiogenic properties of metronomic topotecan in ovarian carcinoma

Purpose: Metronomic chemotherapy regimens have shown anti-tumor activity by anti-angiogenic mechanisms, however, the efficacy of metronomic topotecan in ovarian cancer is not known and the focus of the current study.   Experimental Design: In vivo dose-finding and therapy experiments with oral metro...

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主要な著者: Merritt, William M., Danes, Christopher G., Shahzad, Mian M.K., Lin, Yvonne G., Kamat, Aparna A., Han, Liz Y., Spannuth, Whitney A., Nick, Alpa M., Mangala, Lingegowda S., Stone, Rebecca L., Kim, Hye Sun, Gershenson, David M., Jaffe, Robert B., Coleman, Robert L., Chandra, Joya, Sood, Anil K.
フォーマット: Artigo
言語:Inglês
出版事項: Landes Bioscience 2009
主題:
Research Paper
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916970/
https://ncbi.nlm.nih.gov/pubmed/19738426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.8.16.9004
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