Establishment and Characterization of the First Pediatric Adrenocortical Carcinoma Xenograft Model Identifies Topotecan as a Potential Chemotherapeutic Agent

PURPOSE: Pediatric adrenocortical carcinoma (ACC) is a rare and highly aggressive malignancy. Conventional chemotherapeutic agents have shown limited utility and are largely ineffective in treating children with advanced ACC. The lack of cell lines and animal models of pediatric ACC has hampered the...

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Main Authors: Pinto, Emilia M., Morton, Christopher, Rodriguez-Galindo, Carlos, McGregor, Lisa, Davidoff, Andrew M., Mercer, Kimberly, Debelenko, Larisa V., Billups, Catherine, Ribeiro, Raul C., Zambetti, Gerard P.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2013
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3618554/
https://ncbi.nlm.nih.gov/pubmed/23406775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-3354
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