Establishment and Characterization of the First Pediatric Adrenocortical Carcinoma Xenograft Model Identifies Topotecan as a Potential Chemotherapeutic Agent

PURPOSE: Pediatric adrenocortical carcinoma (ACC) is a rare and highly aggressive malignancy. Conventional chemotherapeutic agents have shown limited utility and are largely ineffective in treating children with advanced ACC. The lack of cell lines and animal models of pediatric ACC has hampered the...

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Główni autorzy: Pinto, Emilia M., Morton, Christopher, Rodriguez-Galindo, Carlos, McGregor, Lisa, Davidoff, Andrew M., Mercer, Kimberly, Debelenko, Larisa V., Billups, Catherine, Ribeiro, Raul C., Zambetti, Gerard P.
Format: Artigo
Język:Inglês
Wydane: 2013
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Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3618554/
https://ncbi.nlm.nih.gov/pubmed/23406775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-3354
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