Prion Protein Is Decreased in Alzheimer's Brain and Inversely Correlates with BACE1 Activity, Amyloid-β Levels and Braak Stage

The cellular prion protein (PrP(C)) has been implicated in the development of Alzheimer's disease (AD). PrP(C) decreases amyloid-β (Aβ) production, which is involved in AD pathogenesis, by inhibiting β-secretase (BACE1) activity. Contactin 5 (CNTN5) has also been implicated in the development o...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Whitehouse, Isobel J., Miners, J. Scott, Glennon, Elizabeth B. C., Kehoe, Patrick G., Love, Seth, Kellett, Katherine A. B., Hooper, Nigel M.
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2013
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3618446/
https://ncbi.nlm.nih.gov/pubmed/23577068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059554
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים