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Cellular Prion Protein Expression Is Not Regulated by the Alzheimer's Amyloid Precursor Protein Intracellular Domain

There is increasing evidence of molecular and cellular links between Alzheimer's disease (AD) and prion diseases. The cellular prion protein, PrP(C), modulates the post-translational processing of the AD amyloid precursor protein (APP), through its inhibition of the β-secretase BACE1, and oligo...

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書誌詳細
主要な著者: Lewis, Victoria, Whitehouse, Isobel J., Baybutt, Herbert, Manson, Jean C., Collins, Steven J., Hooper, Nigel M.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283671/
https://ncbi.nlm.nih.gov/pubmed/22363722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031754
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