ロード中...
Ablation of Prion Protein in Wild Type Human Amyloid Precursor Protein (APP) Transgenic Mice Does Not Alter The Proteolysis of APP, Levels of Amyloid-β or Pathologic Phenotype
The cellular prion protein (PrP(C)) has been proposed to play an important role in the pathogenesis of Alzheimer’s disease. In cellular models PrP(C) inhibited the action of the β-secretase BACE1 on wild type amyloid precursor protein resulting in a reduction in amyloid-β (Aβ) peptides. Here we have...
保存先:
| 出版年: | PLoS One |
|---|---|
| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2016
|
| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4957828/ https://ncbi.nlm.nih.gov/pubmed/27447728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159119 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|