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Donor DNA Utilization During Gene Targeting with Zinc-Finger Nucleases
Gene targeting is the term commonly applied to experimental gene replacement by homologous recombination (HR). This process is substantially stimulated by a double-strand break (DSB) in the genomic target. Zinc-finger nucleases (ZFNs) are targetable cleavage reagents that provide an effective means...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Genetics Society of America
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3618352/ https://ncbi.nlm.nih.gov/pubmed/23550125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.112.005439 |
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