Topological and Functional Characterization of the ssSPTs, Small Activating Subunits of Serine Palmitoyltransferase

The topological and functional organization of the two isoforms of the small subunits of human serine palmitoyltransferase (hssSPTs) that activate the catalytic hLCB1/hLCB2 heterodimer was investigated. A variety of experimental approaches placed the N termini of the ssSPTs in the cytosol, their C t...

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Hlavní autoři: Harmon, Jeffrey M., Bacikova, Dagmar, Gable, Kenneth, Gupta, Sita D., Han, Gongshe, Sengupta, Nivedita, Somashekarappa, Niranjanakumari, Dunn, Teresa M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2013
Témata:
Lipids
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617257/
https://ncbi.nlm.nih.gov/pubmed/23426370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.451526
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