A Disease-causing Mutation in the Active Site of Serine Palmitoyltransferase Causes Catalytic Promiscuity

Por Gable, Kenneth, Gupta, Sita D., Han, Gongshe, Niranjanakumari, Somashekarappa, Harmon, Jeffrey M., Dunn, Teresa M.
Publicado em 2010

Tsc10p and FVT1: topologically distinct short-chain reductases required for long-chain base synthesis in yeast and mammals

Por Gupta, Sita D., Gable, Kenneth, Han, Gongshe, Borovitskaya, Anna, Selby, Luke, Dunn, Teresa M., Harmon, Jeffrey M.
Publicado em 2009

Expression of the ORMDLS, Modulators of Serine Palmitoyltransferase, Is Regulated by Sphingolipids in Mammalian Cells

Por Gupta, Sita D., Gable, Kenneth, Alexaki, Aikaterini, Chandris, Panagiotis, Proia, Richard L., Dunn, Teresa M., Harmon, Jeffrey M.
Publicado no J Biol Chem (2015)

Topological and Functional Characterization of the ssSPTs, Small Activating Subunits of Serine Palmitoyltransferase

Por Harmon, Jeffrey M., Bacikova, Dagmar, Gable, Kenneth, Gupta, Sita D., Han, Gongshe, Sengupta, Nivedita, Somashekarappa, Niranjanakumari, Dunn, Teresa M.
Publicado em 2013

The Pyridoxal 5′-Phosphate (PLP)-Dependent Enzyme Serine Palmitoyltransferase (SPT): Effects of the Small Subunits and Insights from Bacterial Mimics of Human hLCB2a HSAN1 Mutation...

Por Beattie, Ashley E., Gupta, Sita D., Frankova, Lenka, Kazlauskaite, Agne, Harmon, Jeffrey M., Dunn, Teresa M., Campopiano, Dominic J.
Publicado em 2013

Autophagy regulates sphingolipid levels in the liver

Por Alexaki, Aikaterini, Gupta, Sita D., Majumder, Saurav, Kono, Mari, Tuymetova, Galina, Harmon, Jeffrey M., Dunn, Teresa M., Proia, Richard L.
Publicado no J Lipid Res (2014)

Identification of small subunits of mammalian serine palmitoyltransferase that confer distinct acyl-CoA substrate specificities

Por Han, Gongshe, Gupta, Sita D., Gable, Kenneth, Niranjanakumari, Somashekarappa, Moitra, Prasun, Eichler, Florian, Brown, Robert H., Harmon, Jeffrey M., Dunn, Teresa M.
Publicado em 2009

Sphingolipids in the Root Play an Important Role in Regulating the Leaf Ionome in Arabidopsis thaliana([W])([OA])

Por Chao, Dai-Yin, Gable, Kenneth, Chen, Ming, Baxter, Ivan, Dietrich, Charles R., Cahoon, Edgar B., Guerinot, Mary Lou, Lahner, Brett, Lü, Shiyou, Markham, Jonathan E., Morrissey, Joe, Han, Gongshe, Gupta, Sita D., Harmon, Jeffrey M., Jaworski, Jan G., Dunn, Teresa M., Salt, David E.
Publicado em 2011

Overexpression of the Wild-Type SPT1 Subunit Lowers Desoxysphingolipid Levels and Rescues the Phenotype of HSAN1

Por Eichler, Florian S., Hornemann, Thorsten, McCampbell, Alex, Kuljis, Dika, Penno, Anke, Vardeh, Daniel, Tamrazian, Eric, Garofalo, Kevin, Lee, Ho-Joon, Kini, Lohit, Selig, Martin, Frosch, Matthew, Gable, Ken, von Eckardstein, Arnold, Woolf, Clifford J., Guan, Guiman, Harmon, Jeffrey M., Dunn, Teresa M., Brown, Robert H.
Publicado em 2009