Effects of the nitric oxide donor JS-K on the blood-tumor barrier and on orthotopic U87 rat gliomas assessed by MRI

Nitric oxide (NO) released from NO donors can be cytotoxic in tumor cells and can enhance the transport of drugs into brain tumors by altering blood-tumor barrier permeability. The NO donor JS-K [O(2)-(2,4-dinitrophenyl) 1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate] releases NO upon...

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Autori principali: Weidensteiner, Claudia, Reichardt, Wilfried, Shami, Paul J., Saavedra, Joseph E., Keefer, Larry K., Baumer, Brunhilde, Werres, Anna, Jasinski, Robert, Osterberg, Nadja, Weyerbrock, Astrid
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617040/
https://ncbi.nlm.nih.gov/pubmed/23370169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.niox.2013.01.003
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