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Making the cut: intramembrane cleavage by a rhomboid protease promotes ERAD
Endoplasmic reticulum–associated degradation (ERAD) is a cellular protein quality-control process that disposes of proteasomal substrates from the early secretory pathway. Recent work shows that the endoplasmic reticulum–resident rhomboid protease RHBDL4 facilitates ERAD by recognizing and cleaving...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3616633/ https://ncbi.nlm.nih.gov/pubmed/23037595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2398 |
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