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m-AAA protease-driven membrane dislocation allows intramembrane cleavage by rhomboid in mitochondria

Maturation of cytochrome c peroxidase (Ccp1) in mitochondria occurs by the subsequent action of two conserved proteases in the inner membrane: the m-AAA protease, an ATP-dependent protease degrading misfolded proteins and mediating protein processing, and the rhomboid protease Pcp1, an intramembrane...

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Autores principales: Tatsuta, Takashi, Augustin, Steffen, Nolden, Mark, Friedrichs, Björn, Langer, Thomas
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783466/
https://ncbi.nlm.nih.gov/pubmed/17245427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601514
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