Rescue of Impaired NK Cell Activity in Hodgkin Lymphoma With Bispecific Antibodies In Vitro and in Patients

Natural killer (NK) cells represent a key component of the innate immune system against cancer. Nevertheless, malignant diseases arise in immunocompetent individuals despite tumor immunosurveillance. Hodgkin lymphoma (HL) is characterized by CD30(+) tumor cells and a massive infiltration of immune e...

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Main Authors: Reiners, Katrin S., Kessler, Jörg, Sauer, Maike, Rothe, Achim, Hansen, Hinrich P., Reusch, Uwe, Hucke, Christian, Köhl, Ulrike, Dürkop, Horst, Engert, Andreas, von Strandmann, Elke Pogge
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2013
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616527/
https://ncbi.nlm.nih.gov/pubmed/23459515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.14
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