Heredity and cardiometabolic risk: naturally occurring polymorphisms in the human neuropeptide Y(2) receptor promoter disrupt multiple transcriptional response motifs

OBJECTIVES: The neuropeptide Y(2) G-protein-coupled receptor (NPY2R) relays signals from PYY or neuropeptide Y toward satiety and control of body mass. Targeted ablation of the NPY2R locus in mice yields obesity, and studies of NPY2R promoter genetic variation in more than 10 000 human participants...

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Detalhes bibliográficos
Main Authors: Wei, Zhiyun, Zhang, Kuixing, Wen, Gen, Balasubramanian, Karthika, Shih, Peian B., Rao, Fangwen, Friese, Ryan S., Miramontes-Gonzalez, Jose P., Schmid-Schoenbein, Geert W., Kim, Hyung-Suk, Mahata, Sushil K., O’Connor, Daniel T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615981/
https://ncbi.nlm.nih.gov/pubmed/23149563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HJH.0b013e32835b053d
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