Neuropeptide Y(1) receptor NPY1R: Discovery of naturally occurring human genetic variants governing gene expression in cella as well as pleiotropic effects on autonomic activity and blood pressure in vivo

BACKGROUND: Neuropeptide Y (NPY) interacts with the Y(1) receptor, NPY1R, to control adrenergic activity and BP. We asked whether naturally occurring genetic variation at the human NPY1R locus alters autonomic traits that might predispose individuals to cardiovascular disease. METHODS AND RESULTS: W...

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Detalhes bibliográficos
Main Authors: Wang, Lei, Rao, Fangwen, Zhang, Kuixing, Mahata, Manjula, Rodriguez-Flores, Juan L., Fung, Maple M., Waalen, Jill, Cockburn, Myles G., Hamilton, Bruce A., Mahata, Sushil K., O'Connor., Daniel T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2792636/
https://ncbi.nlm.nih.gov/pubmed/19712806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2009.05.035
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