Proteomic Analysis Yields an Unexpected Trans-Acting Point in Control of the Human Sympathochromaffin Phenotype

BACKGROUND: The secretory protein chromogranin A (CHGA) plays a necessary role in formation of catecholamine storage vesicles and also gives rise to a catecholamine release-inhibitory fragment. Since genetic variation in the proximal human CHGA promoter predicts autonomic function and blood pressure...

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Main Authors: Chiron, Stephane, Wei, Zhiyun, Chen, Yuqing, Zhang, Kuixing, Wen, Gen, Fischer, Wolfgang H., Mahata, Sushil K., O’Connor, Daniel T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319683/
https://ncbi.nlm.nih.gov/pubmed/21551321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.110.957886
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