Potential Roles of CCR5(+) CCR6(+) Dendritic Cells Induced by Nasal Ovalbumin plus Flt3 Ligand Expressing Adenovirus for Mucosal IgA Responses

We assessed the role of CCR5(+)/CCR6(+)/CD11b(+)/CD11c(+) dendritic cells (DCs) for induction of ovalbumin (OVA)-specific antibody (Ab) responses following mucosal immunization. Mice given nasal OVA plus an adenovirus expressing Flt3 ligand (Ad-FL) showed early expansion of CCR5(+)/CCR6(+)/CD11b(+)/...

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Bibliographic Details
Main Authors: Fukuyama, Yoshiko, Tokuhara, Daisuke, Sekine, Shinichi, Aso, Kazuyoshi, Kataoka, Kosuke, Davydova, Julia, Yamamoto, Masato, Gilbert, Rebekah S., Tokuhara, Yuka, Fujihashi, Keiko, Kunisawa, Jun, Yuki, Yoshikazu, Kiyono, Hiroshi, McGhee, Jerry R., Fujihashi, Kohtaro
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615010/
https://ncbi.nlm.nih.gov/pubmed/23565250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060453
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