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Stochastic humoral immunity to Bacillus anthracis Protective Antigen: Identification of anti-peptide IgG correlating with seroconversion to Lethal Toxin neutralization

A substantial fraction of individuals vaccinated against anthrax have low to immeasurable levels of serum Lethal Toxin (LeTx)-neutralizing activity. The only known correlate of protection against Bacillus anthracis in the currently licensed vaccine is magnitude of the IgG response to Protective Anti...

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Detalhes bibliográficos
Main Authors: Dumas, Eric K., Nguyen, Melissa L., Cox, Philip M., Rodgers, Heidi, Peterson, Joanne L., James, Judith A., Farris, A. Darise
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614092/
https://ncbi.nlm.nih.gov/pubmed/23415781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2013.01.040
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