Anthrax Vaccination Induced Anti-Lethal Factor IgG: Fine Specificity and Neutralizing Capacity

The efficacy biomarker of the currently licensed anthrax vaccine (AVA) is based on quantity and neutralizing capacity of anti-Protective Antigen (anti-PA) antibodies. However, animal studies have demonstrated that antibodies to Lethal Factor (LF) can provide protection against in vivo bacterial spor...

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Main Authors: Crowe, Sherry R., Garman, Lori, Engler, Renata J.M., Farris, A. Darise, Ballard, Jimmy D., Harley, John B., James, Judith A.
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233230/
https://ncbi.nlm.nih.gov/pubmed/21420416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.03.011
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