Sequential B-Cell Epitopes of Bacillus anthracis Lethal Factor Bind Lethal Toxin-Neutralizing Antibodies

The bipartite anthrax lethal toxin (LeTx) consisting of protective antigen (PA) and lethal factor (LF) is a major virulence factor contributing to death from systemic Bacillus anthracis infection. The current vaccine elicits antibodies directed primarily to PA; however, in experimental settings sero...

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Main Authors: Nguyen, Melissa L., Crowe, Sherry R., Kurella, Sridevi, Teryzan, Simon, Cao, Brian, Ballard, Jimmy D., James, Judith A., Farris, A. Darise
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2009
Teme:
Microbial Immunity and Vaccines
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612257/
https://ncbi.nlm.nih.gov/pubmed/18981257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00788-08
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