Resistance of Human Alveolar Macrophages to Bacillus anthracis Lethal Toxin

The etiologic agent of inhalational anthrax, B. anthracis, produces virulence toxins that are important in the disease pathogenesis. Current studies suggest that mouse and human macrophages are susceptible to immunosuppressive effects of one of the virulence toxins, lethal toxin (LT). Thus a paradig...

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Main Authors: Wu, Wenxin, Mehta, Harshini, Chakrabarty, Kaushik, Booth, J. Leland, Duggan, Elizabeth S., Patel, Krupa B., Ballard, Jimmy D., Coggeshall, K. Mark, Metcalf, Jordan P.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770336/
https://ncbi.nlm.nih.gov/pubmed/19812208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803406
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