MHC Class II and Non-MHC Class II Genes Differentially Influence Humoral Immunity to Bacillus anthracis Lethal Factor and Protective Antigen

Anthrax Lethal Toxin consists of Protective Antigen (PA) and Lethal Factor (LF), and current vaccination strategies focus on eliciting antibodies to PA. In human vaccination, the response to PA can vary greatly, and the response is often directed toward non-neutralizing epitopes. Variable vaccine re...

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Detalhes bibliográficos
Main Authors: Garman, Lori, Dumas, Eric K., Kurella, Sridevi, Hunt, Jonathan J., Crowe, Sherry R., Nguyen, Melissa L., Cox, Philip M., James, Judith A., Farris, A. Darise
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528256/
https://ncbi.nlm.nih.gov/pubmed/23342680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins4121451
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