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MHC Class II and Non-MHC Class II Genes Differentially Influence Humoral Immunity to Bacillus anthracis Lethal Factor and Protective Antigen

Anthrax Lethal Toxin consists of Protective Antigen (PA) and Lethal Factor (LF), and current vaccination strategies focus on eliciting antibodies to PA. In human vaccination, the response to PA can vary greatly, and the response is often directed toward non-neutralizing epitopes. Variable vaccine re...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Garman, Lori, Dumas, Eric K., Kurella, Sridevi, Hunt, Jonathan J., Crowe, Sherry R., Nguyen, Melissa L., Cox, Philip M., James, Judith A., Farris, A. Darise
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528256/
https://ncbi.nlm.nih.gov/pubmed/23342680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins4121451
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