The ZRANB3 translocase associates with poly-ubiquitinated PCNA to promote fork restart and limit recombination after replication stress

Completion of DNA replication after replication stress depends on PCNA, which undergoes mono-ubiquitination to stimulate direct bypass of DNA lesions by specialized DNA polymerases or is poly-ubiquitinated to promote recombination dependent DNA synthesis across DNA lesions by template switching mech...

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Autores principales: Ciccia, Alberto, Nimonkar, Amitabh V., Hu, Yiduo, Hajdu, Ildiko, Achar, Yathish Jagadheesh, Izhar, Lior, Petit, Sarah A., Adamson, Britt, Yoon, John C., Kowalczykowski, Stephen C., Livingston, David M., Haracska, Lajos, Elledge, Stephen J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613862/
https://ncbi.nlm.nih.gov/pubmed/22704558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.05.024
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