Motor neuron degeneration in a mouse model of seipinopathy

Heterozygosity for missense mutations (N88S/S90L) in BSCL2 (Berardinelli–Seip congenital lipodystrophy type 2)/Seipin is associated with a broad spectrum of motoneuron diseases. To understand the underlying mechanisms how the mutations lead to motor neuropathy, we generated transgenic mice with neur...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Guo, J, Qiu, W, Soh, S L Y, Wei, S, Radda, G K, Ong, W-Y, Pang, Z P, Han, W
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2013
Assuntos:
Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613842/
https://ncbi.nlm.nih.gov/pubmed/23470542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.64
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares