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Necroptosis is dispensable for motor neuron degeneration in a mouse model of ALS

Motor neuron degeneration in amyotrophic lateral sclerosis (ALS) is proposed to occur by necroptosis, an inflammatory form of regulated cell death. Prior studies implicated necroptosis in ALS based on accumulation of necroptotic markers in affected tissues of patients and mouse models, and ameliorat...

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Podrobná bibliografie
Vydáno v:Cell Death Differ
Hlavní autoři: Wang, Taide, Perera, Nirma D., Chiam, Mathew D. F., Cuic, Brittany, Wanniarachchillage, Nayomi, Tomas, Doris, Samson, André L., Cawthorne, Wayne, Valor, Eric N., Murphy, James M., Turner, Bradley J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7206015/
https://ncbi.nlm.nih.gov/pubmed/31745214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0457-8
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