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A COMPUTATIONAL MODEL OF MOTOR NEURON DEGENERATION
To explore the link between bioenergetics and motor neuron degeneration, we used a computational model in which detailed morphology and ion conductance are paired with intracellular ATP production and consumption. We found that reduced ATP availability increases the metabolic cost of a single action...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4167823/ https://ncbi.nlm.nih.gov/pubmed/25088365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2014.07.001 |
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