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Targeting Inhibition of Fibroblast Activation Protein-α and Prolyl Oligopeptidase Activities on Cells Common to Metastatic Tumor Microenvironments

Fibroblast activation protein (FAP), a membrane prolyl-specific proteinase with both dipeptidase and endopeptidase activities, is overexpressed by reactive stromal fibroblasts during epithelial-derived cancer growth. FAP digests extracellular matrix as tissue is remodeled during cancer expansion and...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Christiansen, Victoria J, Jackson, Kenneth W, Lee, Kyung N, Downs, Tamyra D, McKee, Patrick A
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Neoplasia Press Inc. 2013
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612908/
https://ncbi.nlm.nih.gov/pubmed/23555181
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