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The effect of a single nucleotide polymorphism on human α(2)-antiplasmin activity
The primary inhibitor of plasmin, α(2)-antiplasmin (α(2)AP), is secreted by the liver into plasma with Met as the amino-terminus. During circulation, Met-α(2)AP is cleaved by antiplasmin-cleaving enzyme (APCE), yielding Asn-α(2)AP, which is crosslinked into fibrin approximately 13 times faster than...
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| Glavni autori: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society of Hematology
2007
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1890835/ https://ncbi.nlm.nih.gov/pubmed/17317851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-01-065185 |
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