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Non-Covalent Interaction of α(2)-Antiplasmin with Fibrin(ogen): Localization of α(2)-Antiplasmin Binding Sites

Covalent incorporation (cross-linking) of plasmin inhibitor α(2)-antiplasmin (α(2)-AP) into fibrin clots increases their resistance to fibrinolysis. We hypothesized that α(2)-AP may also interact non-covalently with fibrin prior to its covalent cross-linking. To test this hypothesis, we studied bind...

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Detalhes bibliográficos
Main Authors: Tsurupa, Galina, Yakovlev, Sergiy, McKee, Patrick, Medved, Leonid
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932838/
https://ncbi.nlm.nih.gov/pubmed/20687529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1010317
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