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Using Substrate Specificity of Antiplasmin-Cleaving Enzyme for Fibroblast Activation Protein Inhibitor Design()

Circulating antiplasmin-cleaving enzyme (APCE), a prolyl-specific serine proteinase, is essentially identical to membrane-inserted fibroblast activation protein (FAP) that is transiently expressed during epithelial-derived cancer growth. Human precursive α(2)-antiplasmin (Met-α(2)AP), the only known...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Lee, Kyung N., Jackson, Kenneth W., Terzyan, Simon, Christiansen, Victoria J., McKee, Patrick A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4470291/
https://ncbi.nlm.nih.gov/pubmed/19402713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900257m
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