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Stem cell-derived hepatocytes as a predictive model for drug-induced liver injury: are we there yet?

Amongst the different types of adverse drug reactions, drug-induced liver injury is the most prominent cause of patient morbidity and mortality. However, the current available hepatic model systems developed for evaluating safety have limited utility and relevance as they do not fully recapitulate a...

詳細記述

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書誌詳細
主要な著者: Kia, Richard, Sison, Rowena L C, Heslop, James, Kitteringham, Neil R, Hanley, Neil, Mills, John S, Park, B Kevin, Goldring, Chris E P
フォーマット: Artigo
言語:Inglês
出版事項: Blackwell Science Inc 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612706/
https://ncbi.nlm.nih.gov/pubmed/22703588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2012.04360.x
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