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DNA polymerase β variant Ile260Met generates global gene expression changes related to cellular transformation
Maintenance of genomic stability is essential for cellular survival. The base excision repair (BER) pathway is critical for resolution of abasic sites and damaged bases, estimated to occur 20,000 times in cells daily. DNA polymerase β (Pol β) participates in BER by filling DNA gaps that result from...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2012
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3611876/ https://ncbi.nlm.nih.gov/pubmed/22914675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/mutage/ges034 |
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