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DNA polymerase β variant Ile260Met generates global gene expression changes related to cellular transformation

Maintenance of genomic stability is essential for cellular survival. The base excision repair (BER) pathway is critical for resolution of abasic sites and damaged bases, estimated to occur 20,000 times in cells daily. DNA polymerase β (Pol β) participates in BER by filling DNA gaps that result from...

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Détails bibliographiques
Auteurs principaux: Donigan, Katherine A., Tuck, David, Schulz, Vince, Sweasy, Joann B.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3611876/
https://ncbi.nlm.nih.gov/pubmed/22914675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/mutage/ges034
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