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Visualizing and Manipulating Focal Adhesion Kinase Regulation in Live Cells

Focal Adhesion Kinase (FAK) is essential for cell migration and plays an important role in tumor metastasis. However, the complex intermolecular and intramolecular interactions that regulate FAK activity at the focal adhesion remain unresolved. We have engineered a toolbox of FRET sensors that retai...

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Detalhes bibliográficos
Main Authors: Ritt, Michael, Guan, Jun Lin, Sivaramakrishnan, Sivaraj
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610962/
https://ncbi.nlm.nih.gov/pubmed/23393139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.421164
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