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Visualizing and Manipulating Focal Adhesion Kinase Regulation in Live Cells

Focal Adhesion Kinase (FAK) is essential for cell migration and plays an important role in tumor metastasis. However, the complex intermolecular and intramolecular interactions that regulate FAK activity at the focal adhesion remain unresolved. We have engineered a toolbox of FRET sensors that retai...

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Bibliografische gegevens
Hoofdauteurs: Ritt, Michael, Guan, Jun Lin, Sivaramakrishnan, Sivaraj
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610962/
https://ncbi.nlm.nih.gov/pubmed/23393139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.421164
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