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Visualizing and Manipulating Focal Adhesion Kinase Regulation in Live Cells
Focal Adhesion Kinase (FAK) is essential for cell migration and plays an important role in tumor metastasis. However, the complex intermolecular and intramolecular interactions that regulate FAK activity at the focal adhesion remain unresolved. We have engineered a toolbox of FRET sensors that retai...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3610962/ https://ncbi.nlm.nih.gov/pubmed/23393139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.421164 |
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