Elevated PLA2G7 Gene Promoter Methylation as a Gender-Specific Marker of Aging Increases the Risk of Coronary Heart Disease in Females

PLA2G7 gene product is a secreted enzyme whose activity is associated with coronary heart disease (CHD). The goal of our study is to investigate the contribution of PLA2G7 promoter DNA methylation to the risk of CHD. Using the bisulphite pyrosequencing technology, PLA2G7 methylation was measured amo...

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Bibliografiske detaljer
Main Authors: Jiang, Danjie, Zheng, Dawei, Wang, Lingyan, Huang, Yi, Liu, Haibo, Xu, Leiting, Liao, Qi, Liu, Panpan, Shi, Xinbao, Wang, Zhaoyang, Sun, Lebo, Zhou, Qingyun, Li, Ni, Xu, Limin, Le, Yanping, Ye, Meng, Shao, Guofeng, Duan, Shiwei
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610900/
https://ncbi.nlm.nih.gov/pubmed/23555769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059752
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