Elevated PLA2G7 Gene Promoter Methylation as a Gender-Specific Marker of Aging Increases the Risk of Coronary Heart Disease in Females

PLA2G7 gene product is a secreted enzyme whose activity is associated with coronary heart disease (CHD). The goal of our study is to investigate the contribution of PLA2G7 promoter DNA methylation to the risk of CHD. Using the bisulphite pyrosequencing technology, PLA2G7 methylation was measured amo...

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Main Authors: Jiang, Danjie, Zheng, Dawei, Wang, Lingyan, Huang, Yi, Liu, Haibo, Xu, Leiting, Liao, Qi, Liu, Panpan, Shi, Xinbao, Wang, Zhaoyang, Sun, Lebo, Zhou, Qingyun, Li, Ni, Xu, Limin, Le, Yanping, Ye, Meng, Shao, Guofeng, Duan, Shiwei
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610900/
https://ncbi.nlm.nih.gov/pubmed/23555769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059752
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