GCK Gene-Body Hypomethylation Is Associated with the Risk of Coronary Heart Disease

Objectives. Glucokinase encoded by GCK is a key enzyme that facilitates phosphorylation of glucose to glucose-6-phosphate. Variants of GCK gene were shown to be associated with type 2 diabetes (T2D) and coronary heart disease (CHD). The goal of this study was to investigate the contribution of GCK g...

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Autors principals: Xu, Limin, Zheng, Dawei, Wang, Lingyan, Jiang, Danjie, Liu, Haibo, Xu, Leiting, Liao, Qi, Zhang, Lina, Liu, Panpan, Shi, Xinbao, Wang, Zhaoyang, Sun, Lebo, Zhou, Qingyun, Li, Ni, Huang, Yi, Le, Yanping, Ye, Meng, Shao, Guofeng, Duan, Shiwei
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947703/
https://ncbi.nlm.nih.gov/pubmed/24696842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/151723
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