Cisplatin sensitivity is enhanced in non-small cell lung cancer cells by regulating epithelial-mesenchymal transition through inhibition of eukaryotic translation initiation factor 5A2

BACKGROUND: Epithelial-mesenchymal transition (EMT) has been believed to be related with chemotherapy resistance in non-small cell lung cancer (NSCLC). Recent studies have suggested eIF5A-2 may function as a proliferation-related oncogene in tumorigenic processes. METHODS: We used cell viability ass...

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Detalhes bibliográficos
Publicado no:BMC Pulm Med
Main Authors: Xu, Guodong, Yu, Hui, Shi, Xinbao, Sun, Lebo, Zhou, Qingyun, Zheng, Dawei, Shi, Huoshun, Li, Ni, Zhang, Xianning, Shao, Guofeng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232729/
https://ncbi.nlm.nih.gov/pubmed/25380840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2466-14-174
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