Elevated PLA2G7 Gene Promoter Methylation as a Gender-Specific Marker of Aging Increases the Risk of Coronary Heart Disease in Females

PLA2G7 gene product is a secreted enzyme whose activity is associated with coronary heart disease (CHD). The goal of our study is to investigate the contribution of PLA2G7 promoter DNA methylation to the risk of CHD. Using the bisulphite pyrosequencing technology, PLA2G7 methylation was measured amo...

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Autori principali: Jiang, Danjie, Zheng, Dawei, Wang, Lingyan, Huang, Yi, Liu, Haibo, Xu, Leiting, Liao, Qi, Liu, Panpan, Shi, Xinbao, Wang, Zhaoyang, Sun, Lebo, Zhou, Qingyun, Li, Ni, Xu, Limin, Le, Yanping, Ye, Meng, Shao, Guofeng, Duan, Shiwei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610900/
https://ncbi.nlm.nih.gov/pubmed/23555769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059752
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