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Intracranial Injection of AAV Expressing NEP but Not IDE Reduces Amyloid Pathology in APP+PS1 Transgenic Mice
The accumulation of β-amyloid peptides in the brain has been recognized as an essential factor in Alzheimer’s disease pathology. Several proteases, including Neprilysin (NEP), endothelin converting enzyme (ECE), and insulin degrading enzyme (IDE), have been shown to cleave β-amyloid peptides (Aβ). W...
সংরক্ষণ করুন:
| প্রধান লেখক: | , , , , , , , , |
|---|---|
| বিন্যাস: | Artigo |
| ভাষা: | Inglês |
| প্রকাশিত: |
Public Library of Science
2013
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| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3610740/ https://ncbi.nlm.nih.gov/pubmed/23555730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059626 |
| ট্যাগগুলো: |
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