β-amyloid deposition is shifted to the vasculature and memory impairment is exacerbated when hyperhomocysteinemia is induced in APP/PS1 transgenic mice

INTRODUCTION: Vascular dementia is the second most common cause of dementia after Alzheimer’s disease (AD). In addition, it is estimated that almost half of all AD patients have significant cerebrovascular disease comorbid with their AD pathology. We hypothesized that cerebrovascular disease signifi...

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Detalhes bibliográficos
Main Authors: Sudduth, Tiffany L, Weekman, Erica M, Brothers, Holly M, Braun, Kaitlyn, Wilcock, Donna M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4078260/
https://ncbi.nlm.nih.gov/pubmed/24991237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/alzrt262
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