Determining the role of IL-4 induced neuroinflammation in microglial activity and amyloid-β using BV2 microglial cells and APP/PS1 transgenic mice

BACKGROUND: Microglia are considered the resident immune cells of the central nervous system (CNS). In response to harmful stimuli, an inflammatory reaction ensues in which microglia are activated in a sequenced spectrum of pro- and antiinflammatory phenotypes that are akin to the well-characterized...

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Vydáno v:J Neuroinflammation
Hlavní autoři: Latta, Clare H, Sudduth, Tiffany L, Weekman, Erica M, Brothers, Holly M, Abner, Erin L, Popa, Gabriel J, Mendenhall, Michael D, Gonzalez-Oregon, Floracita, Braun, Kaitlyn, Wilcock, Donna M
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350455/
https://ncbi.nlm.nih.gov/pubmed/25885682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0243-6
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