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Endogenous IL-21 regulates pathogenic mucosal CD4 T-cell responses during enhanced RSV disease in mice
A role for interleukin-21 (IL-21) has recently been found in several diseases, but contribution to mucosal defences has not been described. In BALB/c mice infected with respiratory syncytial virus (RSV), IL-21 depletion had little effect in primary infection. However, depletion of mice during primin...
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Главные авторы: | , , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
Nature Publishing Group
2013
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Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3610641/ https://ncbi.nlm.nih.gov/pubmed/23168836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2012.108 |
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