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TGF-β enhanced IL-21-induced differentiation of human IL-21-producing CD4+ T cells via Smad3.

IL-21 has pleiotropic effects on innate and adaptive immune response, and plays an important role in the development of autoimmune disease and antitumor activity. It has been reported that IL-21 is produced by CD4(+) T cells and NKT cells. However, the differentiation of IL-21-producing CD4(+) T cel...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yun Liu, Sifei Yu, Zitao Li, Jiangjun Ma, Yannan Zhang, Hui Wang, Binyan Yang, Changyou Wu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science (PLoS) 2013-01-01
Cyfres:PLoS ONE
Mynediad Ar-lein:http://europepmc.org/articles/PMC3669387?pdf=render
Tagiau: Ychwanegu Tag
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