TGF-β enhanced IL-21-induced differentiation of human IL-21-producing CD4+ T cells via Smad3.

IL-21 has pleiotropic effects on innate and adaptive immune response, and plays an important role in the development of autoimmune disease and antitumor activity. It has been reported that IL-21 is produced by CD4(+) T cells and NKT cells. However, the differentiation of IL-21-producing CD4(+) T cel...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Yun Liu, Sifei Yu, Zitao Li, Jiangjun Ma, Yannan Zhang, Hui Wang, Binyan Yang, Changyou Wu
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2013-01-01
Edice:PLoS ONE
On-line přístup:http://europepmc.org/articles/PMC3669387?pdf=render
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky