The importance of local mucosal HIV-specific CD8(+) cytotoxic T lymphocytes for resistance to mucosal viral transmission in mice and enhancement of resistance by local administration of IL-12.

Although crucial to mucosal vaccine development, the mechanisms of defense against mucosal viral infection are still poorly understood. Protection, cytotoxic T lymphocytes (CTL), and neutralizing antibodies have all been observed, but cause and effect have been difficult to determine. The ability of...

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Bibliografiska uppgifter
Huvudupphovsmän: Belyakov, I M, Ahlers, J D, Brandwein, B Y, Earl, P, Kelsall, B L, Moss, B, Strober, W, Berzofsky, J A
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1998
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC509161/
https://ncbi.nlm.nih.gov/pubmed/9854042
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