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Transcutaneous immunization induces mucosal CTLs and protective immunity by migration of primed skin dendritic cells

Transcutaneous immunization (TCI), the application of vaccines on the skin, induces robust systemic and mucosal antibodies in animal models and in humans. The means by which mucosal immune responses to vaccine antigens are elicited by TCI has not been well characterized. We examined the effect of TC...

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Главные авторы: Belyakov, Igor M., Hammond, Scott A., Ahlers, Jeffrey D., Glenn, Gregory M., Berzofsky, Jay A.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2004
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC379323/
https://ncbi.nlm.nih.gov/pubmed/15057306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200420261
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